Extra Supplement: Light in Darkness

Photodynamic therapy: a light in the darkness?

Photodynamic therapy (PDT) is used to treat localized premalignant or early malignant disease. This study reports the enhanced, systemic antitumor immune response from PDT, suggesting that it may have a potential role as a therapy to address both local and disseminated disease.

From Darkness into Light: Factors Controlling Photomorphogenesis

A seedling that emerges in darkness follows a developmental program known as skotomorphogenesis (dark development), which is characterized by etiolation, that is, a long, spindly hypocotyl and pale cotyledons and inhibition of chlorophyll and anthocyanin biosynthesis and true leaf development. Upon exposure to light, the seedling switches rapidly to photomorphogenesis (light development); the h...

From Darkness into Light: Factors Controlling Photomorphogenesis

A seedling that emerges in darkness follows a developmental program known as skotomorphogenesis (dark development), which is characterized by etiolation, that is, a long, spindly hypocotyl and pale cotyledons and inhibition of chlorophyll and anthocyanin biosynthesis and true leaf development. Upon exposure to light, the seedling switches rapidly to photomorphogenesis (light development); the h...

Sarcoma nomograms: a light over the darkness

Ocular vasodynamic changes in light and darkness in smokers.

PURPOSE To determine whether smokers have a reduced capacity for increased retinal blood flow velocity in darkness. METHODS The peak systolic flow velocities (V(S)) and end diastolic flow velocities (V(D)) were measured by ultrasound (i.e., color Doppler equipment), in light and darkness in the ophthalmic and central retinal arteries in 20 cigarette smokers and 20 matched nonsmokers. The resi...